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Powerful Efficacy of GCSB-5 Treatment for Improving Fatigue and Motor Function in Multiple Sclerosis (MS): A Randomized Double Blind, Place-bo-Controlled Study  [PDF]
Ji Yun Shin
Open Access Library PrePrints (OALib PrePrints) , 2016, DOI: 10.4236/oalib.preprints.1200150
Abstract:
Multiple Sclerosis (MS) is the most common disability in young adults that requires early symptomatic treatment to prevent long-term disability. Among young adults, MS is the most common central nerv-ous system (CNS) chronic inflammatory illness that is characterized by demyelination in the CNS. However, current disease-modifying treatments are not sufficiently effective for preventing the variety of symptoms during the course of disease.
Predictors of Career Decision Self
Ji-yeon Lee,Yun-jeong Shin
- , 2018, DOI: 10.1177/1069072717692981
Abstract: We examined sex, socioeconomic status (SES), classism, modern sexism, and locus of control as uniquely contributing factors to college students’ career decision self-efficacy. A total of 139 college students participated in the survey, and the hypothesis was tested with hierarchical regression. Results revealed that (a) sex and SES do not significantly contribute to classism and modern sexism to college students’ career decision self-efficacy and (b) classism and modern sexism, internality and luck uniquely contributed to college students’ career decision self-efficacy above and beyond the variances accounted for sex and SES. Results indicate the importance of classism and modern sexism over actual sex and SES in predicting college students’ career decision self-efficacy
Application of Electrocoagulation and Electrolysis on the Precipitation of Heavy Metals and Particulate Solids in Washwater from the Soil Washing  [PDF]
Ho Y. Shim, Kyo S. Lee, Dong S. Lee, Dae S. Jeon, Mi S. Park, Ji S. Shin, Yun K. Lee, Ji W. Goo, Soo B. Kim, Doug Y. Chung
Journal of Agricultural Chemistry and Environment (JACEN) , 2014, DOI: 10.4236/jacen.2014.34015
Abstract: Soil washing, ex situ mechanical technique, is one of the few permanent treatment alternatives to remove metal contaminants from soils by employing physical separation based on mineral processing technologies to remove discrete particles or metal-bearing particles and/or chemical extraction based on leaching or dissolving process to extract the metals from the soils into an aqueous solution. However, washwater remained from soil washing process contains discrete particulate particles along with heavy metals as solution phase to be treated separately, as well as this process can produce large amount of sludge that requires further treatment, slow metal precipitation, poor settling, the aggregation of metal precipitates. Electrical treatments including electrocoagulation and electrolysis can be effective in removing these substances from washwater. This paper reviews the theoretical models in applying electrocoagulation and electrolysis to remove heavy metals and discrete particulate particles in washwater by examining and comparing the status of washwater treatment technologies which have been undertaken, mostly in the US and EU for the period 1990-2012.
Maternal Outcomes According to Placental Position in Placental Previa
Dong Gyu Jang, Ji Sun We, Jae Un Shin, Yun Jin Choi, Hyun Sun Ko, In Yang Park, Jong Chul Shin
International Journal of Medical Sciences , 2011,
Abstract: Purpose: The purpose of this retrospective cohort study was to elucidate whether the location of placenta below uterine incision in cesarean section is important in the development of maternal complications in placenta previa patients. Methods: The study was conducted on 409 patients 414 parturition at 3 hospitals in affiliation with the Catholic Medical Center, Seoul, Korea from May 1999 to December 2009. The subjects were divided to two groups: the group whose placenta was located in the anterior portion of the uterus (anterior group) and the group whose placenta was located in the posterior portion of the uterus (posterior group). And then they are compared to each other. Logistic regression was used to control for confounding factors. Results: In the anterior group, regardless of confounding factors, the incidence of excessive blood loss (OR 2.97; 95% CI: 1.64-5.37), massive transfusion (OR 3.31; 95% CI: 1.33-8.26), placental accreta (OR 2.60, 95% CI: 1.40-4.83), and hysterectomy (OR 3.47, 95% CI: 1.39-8.68) was higher. Conclusion: Sonographic determination of the placental position where its location beneath the uterine incision is very important to predict maternal outcomes in placenta previa patients, and such cases, close attention should be paid for massive hemorrhage.
The Effects of Epigallocatechin-3-Gallate and Mechanical Stimulation on Osteogenic Differentiation of Human Mesenchymal Stem Cells: Individual or Synergistic Effects
Hyun Ju Choi,Jeong Koo Kim,Ji Won Shin,Jung-Woog Shin,Yanru Wu,Yun Gyeong Kang
- , 2017, DOI: 10.1007/s13770-017-0040-7
Abstract: Schematics of experimental procedur
Modulation of Glucose Metabolism by Balanced Deep-Sea Water Ameliorates Hyperglycemia and Pancreatic Function in Streptozotocin-Induced Diabetic Mice
Byung Geun Ha, Jung-Eun Park, Eun Ji Shin, Yun Hee Shon
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0102095
Abstract: The aim of this study was to determine the effects of balanced deep-sea water (BDSW) on hyperglycemia and glucose intolerance in streptozotocin (STZ)-induced diabetic mice. BDSW was prepared by mixing DSW mineral extracts and desalinated water to yield a final hardness of 1000–4000 ppm. Male ICR mice were assigned to 6 groups; mice in each group were given tap water (normal and STZ diabetic groups) or STZ with BDSW of varying hardness (0, 1000, 2000, and 4000 ppm) for 4 weeks. The STZ with BDSW group exhibited lowered fasting plasma glucose levels than the STZ-induced diabetic group. Oral glucose tolerance tests showed that BDSW improves impaired glucose tolerance in STZ-induced diabetic mice. Histopathological evaluation of the pancreas showed that BDSW restores the morphology of the pancreatic islets of Langerhans and increases the secretion of insulin in STZ-induced diabetic mice. Quantitative real-time PCR assay revealed that the expression of hepatic genes involved in gluconeogenesis, glucose oxidation, and glycogenolysis was suppressed, while the expression of the genes involved in glucose uptake, β-oxidation, and glucose oxidation in muscle were increased in the STZ with BDSW group. BDSW stimulated PI3-K, AMPK, and mTOR pathway-mediated glucose uptake in C2C12 myotubes. BDSW increased AMPK phosphorylation in C2C12 myotubes and improved impaired AMPK phosphorylation in the muscles of STZ-induced diabetic mice. Taken together, these results suggest that BDSW is a potential anti-diabetic agent, owing to its ability to suppress hyperglycemia and improve glucose intolerance by modulating glucose metabolism, recovering pancreatic islets of Langerhans and increasing glucose uptake.
Anti-Diabetic Effect of Balanced Deep-Sea Water and Its Mode of Action in High-Fat Diet Induced Diabetic Mice
Byung Geun Ha,Eun Ji Shin,Jung-Eun Park,Yun Hee Shon
Marine Drugs , 2013, DOI: 10.3390/md11114193
Abstract: In this study, we investigated the effects of balanced deep-sea water (BDSW) on hyperglycemia and glucose intolerance in high-fat diet (HFD)-induced diabetic C57BL/6J mice. BDSW was prepared by mixing deep-sea water (DSW) mineral extracts and desalinated water to give a final hardness of 500–2000. Mice given an HFD with BDSW showed lowered fasting plasma glucose levels compared to HFD-fed mice. Oral and intraperitoneal glucose tolerance tests showed that BDSW improves impaired glucose tolerance in HFD-fed mice. Histopathological evaluation of the pancreas showed that BDSW recovers the size of the pancreatic islets of Langerhans, and increases the secretion of insulin and glucagon in HFD-fed mice. Quantitative reverse transcription polymerase chain reaction results revealed that the expression of hepatic genes involved in glucogenesis, glycogenolysis and glucose oxidation were suppressed, while those in glucose uptake, β-oxidation, and glucose oxidation in muscle were increased in mice fed HFD with BDSW. BDSW increased AMP-dependent kinase (AMPK) phosphorylation in 3T3-L1 pre- and mature adipocytes and improved impaired AMPK phosphorylation in the muscles and livers of HFD-induced diabetic mice. BDSW stimulated phosphoinositol-3-kinase and AMPK pathway-mediated glucose uptake in 3T3-L1 adipocytes. Taken together, these results suggest that BDSW has potential as an anti-diabetic agent, given its ability to suppress hyperglycemia and improve glucose intolerance by increasing glucose uptake.
WordRank: Learning Word Embeddings via Robust Ranking
Shihao Ji,Hyokun Yun,Pinar Yanardag,Shin Matsushima,S. V. N. Vishwanathan
Computer Science , 2015,
Abstract: Embedding words in a vector space has gained a lot of research attention in recent years. While state-of-the-art methods provide efficient computation of word similarities via a low-dimensional matrix embedding, their motivation is often left unclear. In this paper, we argue that word embedding can be naturally viewed as a ranking problem. Then, based on this insight, we propose a novel framework WordRank that efficiently estimates word representations via robust ranking. The performance of WordRank is measured in word similarity and word analogy benchmarks, and the results are compared to the state-of-the-art word embedding techniques. Our algorithm produces a vector space with meaningful substructure, as evidenced by its performance of 77.4% accuracy on a popular word similarity benchmark and 76% on the Google word analogy benchmark. WordRank performs especially well on small corpora.
Correlation of Swallowing Function With Bilateral Diaphragmatic Movement in Hemiplegic Stroke Patients
Ho Eun Park,Ji Won Hong,Jin A Yoon,Ra Yu Yun,Yong Beom Shin
- , 2019, DOI: 10.5535/arm.2019.43.2.156
Abstract: To investigate difference in bilateral diaphragm movement of patients with tracheal aspiration according to post stroke residue severity and determine correlations of Penetration-Aspiration Scale (PAS), residue scale, and bilateral diaphragm movement
A Case Report of Recurrent Metastatic Sebaceous Carcinoma Which Showed Favorable Response Tt Non-Fluorouracil Based Chemotherapy
Hyo Jin Park,Ji Yeon Yoo,Shin Hee Lee,Yun Hwa Jung
- , 2018, DOI: 10.12659/AJCR.912552
Abstract:
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